Zbtb7

{{#if: | {{#if: | {{#if:18078| {{#if: 584 Aminosäuren | {{#if: | {{#if: | {{#if: | {{#if: | {{#if: ZBTB7AO95365605878 | {{#if: ZBTB7A | {{#if: O95365605878 | {{#if: | {{#if:| {{#if: | {{#if: | {{#if: | {{#if: | {{#if: | {{#if: | {{#if: | {{#if: | {{#if: Wirbeltiere<ref>Homologe bei OMA</ref>{{#if: O95365 | {{#ifeq: | NV ||1}}|}}| {{#if: O95365 | {{#ifeq: | NV || | style="background:#C3FDB8; color:#000000;" | Homologie-Familie {{#if: Wirbeltiere<ref>Homologe bei OMA</ref> | | style="background:#C3FDB8; color:#000000;" | Übergeordnetes Taxon {{#if: | | style="background:#C3FDB8; color:#000000;" | Ausnahmen {{#if: | }}

{{#if: | | Zbtb7 }}
[[Datei:|250x200px|{{#if: | | Zbtb7 }}]]
Zbtb7 }}
Andere Namen	{{{Andere Namen}}} }}
Vorhandene Strukturdaten: }}
Eigenschaften des menschlichen Proteins }}
Masse/Länge Primärstruktur	584 Aminosäuren }}
Sekundär- bis Quartärstruktur	}}
Kofaktor	}}
Präkursor	}}
Isoformen	}}
Bezeichner
{{#if: | Gen-Namen | Gen-Name}} | Gen-Name(n) }}	{{#if:18078 | ZBTB7A | ZBTB7A}}{{#if: |, }} }}
Externe IDs	{{#if: | GeneCards: Vorlage:GeneCards}}{{#if:605878 | OMIM: 605878}}{{#if:O95365| {{#if: | | UniProt }} {{#if:|{{{titel}}}|O95365}}{{#if:|Vorlage:Abrufdatum}}}}{{#if: | MGI: [1]}}{{#if: | PubChem: {{#switch: {{{PubChem}}}		0 | }}	- = –	valid|1|2=/^[1-9]%d?%d?%d?%d?%d?%d?%d?%d?$/	0 | Wikipedia:Vorlagenfehler/Vorlage:PubChem}}	template= Vorlage:PubChem	format= }} }}{{#invoke:TemplatePar|check	all= 1=	opt= 2=	0 | Wikipedia:Vorlagenfehler/Vorlage:PubChem}}	template= Vorlage:PubChem	format= }}{{#if: {{#invoke:Wikidata|pageId}}||{{#ifeq: 0 | 0 | }} }}}}{{#if: | CAS-Nummer:  }}{{#if: | }} }} }}
Arzneistoffangaben
ATC-Code	}} {{#if:|
DrugBank	[2] }} {{#if:|
Wirkstoffklasse	}} }}
Transporter-Klassifikation
TCDB	[3] {{#if: |
Bezeichnung	}} }}
{{#if:|Inhibitorklassifikation|{{#if:|Enzymklassifikationen|Enzymklassifikation}}}}
EC, Kategorie	{{#if:| [4]}}{{#if: |, [[]]}} }}
MEROPS	[5]}}
MEROPS	[6]}}
Reaktionsart	}}
Substrat	}}
Produkte	}} }}
Vorkommen
{{#if:		[ {{#if:	Hovergen}}]	[http://hogenom.univ-lyon1.fr/query_sequence?seq=O95365 {{#if:	Hovergen}}]}} }} }}
Wirbeltiere<ref>Homologe bei OMA</ref> }}
}} }}

{{#if:||}}

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}}

Zbtb7 (Zinc finger and BTB domain-containing protein 7, ursprünglich Pokemon) ist ein krebsförderndes Protein in Wirbeltieren, welches vom Gen ZBTB7 (mit Lokalisation auf dem Chromosom 19p13.3) kodiert wird.<ref>{{#if: | [[{{{authorlink}}}|Vorlage:Cite book/Name]] | Vorlage:Cite book/Name

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  }}</ref> Die Substanz unterdrückt die Transkription bestimmter Proteine und hemmt so indirekt die Funktion der Tumorsuppressorproteine RB und p53.

Der ursprüngliche Name Pokemon steht für „POK erythroid myeloid ontogenic factor“. POK bezieht sich auf die POK-Familie, zu der das Protein gehört,<ref>Maeda, Hobbs, Pandolfi: The Transcription Factor Pokemon: A New Key Player in Cancer Pathogenesis, Oktober 2005, doi:10.1158/0008-5472.CAN-05-1055.</ref> während ontogenic vermutlich eine Fehlschreibung von oncogenic ‚krebserzeugend‘ ist. Zugleich erinnert der Name – vielleicht absichtlich – an die Pokémon-Serie von Filmen und Spielen. Nach einer Beschwerde von Pokémon USA im Dezember 2005 wurde die Normbezeichnung Pokemon von dem Entdeckerinstitut zurückgezogen, seitdem heißt das Protein Zbtb7.<ref>{{#if:Vorlage:Cite book/URL|{{#iferror: {{#iferror:{{#invoke:Vorlage:FormatDate|Execute}}|}}| |}}}}{{#if:{{#if:

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Einzelnachweise

<references />