Mammorenales Syndrom

Als mammorenales Syndrom wird das gemeinsame Auftreten einer Fehlbildung der Nieren mit der Anlage überzähliger Brustwarzen (Polythelie) bezeichnet. Eine Häufung wurde in einzelnen Familien beschrieben.<ref>{{#invoke:Vorlage:Literatur|f}}{{#if:

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Klinische Bedeutung

Die klinische Bedeutung des Syndroms ist umstritten. Mehrere Studien ergaben keine bzw. nur eine geringe Assoziation von Polythelie und Fehlbildungen des Urogenitalsystems,<ref>{{#invoke:Vorlage:Literatur|f}}{{#if:

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  }}</ref> weswegen geschlossen wurde, dass bei ansonsten klinisch unauffälligen Neugeborenen mit Polythelie weiterführende diagnostische Untersuchungen nicht erforderlich seien.<ref>{{#invoke:Vorlage:Literatur|f}}{{#if: 
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  }}</ref> Andere Autoren belegen eine signifikante Häufung von Nierenfehlbildungen bei Kindern mit Polythelie und fordern deswegen eine eingehende weiterführende Diagnostik in dieser Personengruppe.<ref>{{#invoke:Vorlage:Literatur|f}}{{#if: 
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Einzelnachweise

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